Медицина - скачать книги или читать онлайн. Страница 119

This fourth edition of Abdominal-Pelvic MRI provides the reader with a significant update on earlier works. Modern diagnostic MRI relies on the practitioner's ability to distinguish between diseases through pattern recognition and experience, and this landmark reference provides the most complete coverage of magnetic resonance imaging of the abdomen and pelvis, with particular emphasis on illustrating benign, malignant and inflammatory lesions An established best-seller in this field updated with multiple brand new case figures supplying the reader with high quality examples of diagnoses and anatomy Includes discussion of new sequences, such as diffusion-weighted imaging and a new chapter on MR/PET Describes techniques and tips for controlling motion, including radial acquisition and shorter breath hold acquisition using techniques of multigradient parallel imaging in order to achieve high quality images Offers practice advice and recommendations for contrast agents taking into account patient safety, efficacy, and cost Accompanying digital edition offers rapid search and easy figure download

Since the first edition of Identification of Pathogenic Fungi, there has been incredible progress in the diagnosis, treatment and prevention of fungal diseases: new methods of diagnosis have been introduced, and new antifungal agents have been licensed for use. However, these developments have been offset by the emergence of resistance to several classes of drugs, and an increase in infections caused by fungi with innate resistance to one or more classes. Identification of Pathogenic Fungi, Second Edition, assists in the identification of over 100 of the most significant organisms of medical importance. Each chapter is arranged so that the descriptions for similar organisms may be found on adjacent pages. Differential diagnosis details are given for each organism on the basis of both colonial appearance and microscopic characteristics for the organisms described. In this fully updated second edition, a new chapter on the identification of fungi in histopathological sections and smears has been added, while colour illustrations of cultures and microscopic structures have been included, and high quality, four colour digital images are incorporated throughout.

Designed as a practical, succinct guide, for quick reference by clinicians with everyday questions, this title guides the reader through the range of approaches available for diagnosis, management, or prevention of hemorrhagic and thrombotic diseases or disorders. Provides essential practical management for all those working in the field of hemostasis and thrombosis Includes new chapters on direct oral anticoagulants, acquired inhibitors of coagulation, and expanded discussion of thrombotic microangiopathies Covers in a clear and succinct format, the diagnosis, treatment and prevention of thrombotic and haemostatic disorders Follows templated chapter formats for rapid referral, including key points and summary boxes, and further reading Highlights controversial issues and provides advice for everyday questions encountered in the clinic

Morphology of Blood Disorders, 2nd edition is an outstanding atlas with over 800 high-quality digital images, covering the whole spectrum of blood and bone marrow morphology, with particular emphasis on malignant haematology. Originally written in the Italian language by two world leaders in the field, the book has been expertly translated by the renowned haematologist and teacher, Barbara Bain. This book explores the major topics of haematological pathology, blending classical teaching with up-to-date WHO classification and terminology. Each image in this book is derived from material obtained for diagnostic purposes from patients with serious haematological conditions. Morphological details are supplemented by detailed descriptions of the output and role of automated instruments in disorders of the blood. Morphology of Blood Disorders, 2nd edition is an essential reference source for diagnosis in the haematology laboratory, designed to be the go-to guide for anyone with an interest in blood cell morphology.

The last decade has seen an upsurge of information on the role of immune responses in neurodegenerative disorders. In many of these diseases it is still unclear whether the innate and adaptive responses are pathogenic or play a role in repair, and thus understanding their precise roles is key to controlling these diseases by designing immune-therapeutic approaches. The connection between many neurological diseases is the realisation that the immune and nervous systems are inextricable linked, and that perturbations in this delicate balance are involved in many disorders. This has opened up new avenues for therapeutic approaches to treatment of CNS inflammatory and neurodegenerative disorders. Neuroinflammation and CNS Disorders brings together the very latest information on the interactions between the immune system and central nervous system. The first section of the book highlights the basic concepts in the field whilst the second section, the main body of the book, covers the role of the immune response in specific disorders of the central nervous system. Neuroinflammation and CNS Disorders will provide an invaluable guide for both researchers and clinicians working in this complex and dynamic field.

Gracey’s Meat Hygiene, Eleventh Edition is the definitive reference for veterinarians working in meat hygiene control. This new edition of a classic text reflects the recent significant changes in science, legislation and practical implementation of meat hygiene controls in the UK, Europe and worldwide since the 10th edition was published in 1999. An excellent practical guide for teaching food hygiene to veterinary students worldwide, in addition to laying the foundations of food animal anatomy, pathology and disease. New chapters address the increased concern of both the public and inspectors to issues of animal welfare and recognise the role of the profession, and interest from the consumer, in environmental protection. Key features include: Fully updated new edition, in a refreshed design with colour photographs and illustrations throughout. Includes new content on meat hygiene inspection covering the components of an integrated food safety management system as well as animal health and welfare controls in the ‘farm to fork’ system. A practical approach to health and safety in meat processing is outlined by identifying the hazards and then describing how these can best be controlled. With contributions from veterinary and industry experts, this edition is both a valuable teaching aid and a practical reference for veterinarians and all food business operators and their staff.

Contemporary Debates in Bioethics features a timely collection of highly readable, debate-style arguments contributed by many of today’s top bioethics scholars, focusing on core bioethical concerns of the twenty-first century. Written in an engaging, debate-style format for accessibility to non-specialists Features general introductions to each topic that precede scholarly debates Presents the latest, cutting-edge thoughts on relevant bioethics ideas, arguments, and debates

Dental caries has been called a “silent epidemic” and is the most prevalent chronic disease affecting children. Though much has been written on the science and practice of managing this disease, publications are diverse in their loci, preventing easy access to the reader. Early Childhood Oral Health coalesces all the important information related to this topic in a comprehensive reference for students, academics, and practitioners. This second edition expands the scope of the first and puts an additional focus on interprofessional and global efforts that are necessary to manage the growing disease crisis and screening and risk assessment efforts that have expanded with the boom of new technologies. With updated references and incorporating the latest research, chapters address the biology and epidemiology of caries, the clinical management of early childhood caries, risk assessment, and early diagnosis. Other topics include public health approaches to managing caries worldwide, implementation of new caries prevention programs, fluoride regimens, and community programs, and family oral health education. Brand new are four chapters on the medical management of early childhood caries, considerations for children with special needs, interprofessional education and practice, and how the newest policy issues and the Affordable Care Act affect dental care. A must-read for pediatric dentists, cariologists, public health dentists, and students in these fields, Early Childhood Oral Health is also relevant for pediatricians and pediatric nursing specialists worldwide.

This case-based clinical text is an exhaustive review of orthodontic problems in the vertical dimension, with evidence-based guidelines for successful diagnosis and treatment. A total of 21 cases address dental deep bites, skeletal deep bites, dental open bites, skeletal open bites, and posterior open bites. Each case includes pretreatment, interim, and posttreatment orthodontic records, as well as references to provide a solid evidence base for decision making. Written with a clinical focus, Orthodontics in the Vertical Dimension is ideal for the practicing orthodontist and makes an excellent resource for residents in pursuit of board certification. Key Features • Detailed case-based scenarios for treatment of the spectrum of open bites and deep bites • Cases presented in question and answer format to encourage thought • 2500 clinical photographs and illustrations. “This is a great textbook, and I will use it in my classes. Highly organized and elaborately illustrated, the authors’ work is inspired by problem-based learning and stimulates cognitive processes by encouraging critical thinking. Their text deserves a ‘must read’ category for orthodontic professionals of all ages.” Dr. Jeryl D. English DDS, MS, Chairman and Graduate Program Director, Department of Orthodontics, The University of Texas Health Science Center at Houston “A terrific book for students of orthodontics and dentofacial orthopedics, covering the vertical dimension and much more. A wide range of cases are presented, treatment plans are realistic, and the authors openly discuss complications encountered during treatment.” Dr. Greg J. Huang, DMD, MSD, MPH Professor and Chair Department of Orthodontics, The University of Washington School of Dentistry “This comprehensive text prepares the reader in the context of a mini-residency with a question answer teaching style. Resident and experienced orthodontists can match their cases with fully worked up patients and alternative treatment options. Well written.” Dr. Katherine L. Vig, BDS, MS, FDS, D.Orth Professor Emeritus and Former Head of Orthodontics, The Ohio State University College of Dentistry

Expert teaching in the fundamentals of oral and maxillofacial surgery Essentials of Oral and Maxillofacial Surgery is the key textbook for all undergraduate dentistry students and trainees starting out in oral and maxillofacial surgery, oral surgery and surgical dentistry. Condensed and revised from the major reference work Oral and Maxillofacial Surgery, all revisions have been made by the editors in order to bring the text up-to-date and accessible for a student audience. The book's coverage extends from basic principles such as patient evaluation, radiographic imaging, and surgical instruments, to specific conditions and procedures, from tooth extraction and endodontic surgery to trauma, implants, dentofacial deformities and orofacial pain. It also offers: A companion website with downloadable figures and MCQs to test your knowledge Over 600 colour photographs, radiographs and explanatory line drawings to illuminate the text Contributions from an international group of authors, distilled by an expert editor team

Bringing a new drug to market is a costly time-consuming process. Increased regional and international regulation over the last twenty years, while necessary, has only served to amplify these costs. In response to this escalation, developmental strategies have shifted towards a more global approach. In order to create the most cost-effective and safe processes, it is critical for those bringing drugs to market to understand both the globally accepted regulations and the local variations. Nonclinical Safety Assessment: A Guide to International Pharmaceutical Regulations provides a practical description of nonclinical drug development regulations and requirements in the major market regions. It includes: ICH – the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use National regulations, including US FDA, Canada, Mercosur and Brazil, South Africa, China, Japan, India and Australia Repeated dose toxicity studies Carcinogenicity; Genotoxicity; Developmental and reproductive toxicology; Immunotoxicology Biotechnology-derived pharmaceuticals Vaccine development Phototoxicity and photocarcinogenicity Degradants, impurities, excipients and metabolites Primarily intended for those professionals actively involved in the nonclinical and clinical development of a pharmaceutical product, including toxicologists, pharmacologists, clinicians and project managers, this book provides a roadmap for successful new drug approval and marketing.

With a growing population of young patients with congenital heart disease reaching adulthood, this unique new book offers an in-depth guide to managing the challenges and issues related to device therapy in this patient group. The only book resource dedicated to pacing, cardiac resynchronization therapy and ICD therapy for the pediatric and congenital heart disease patient Contains practical advice for pacemaker and ICD implantation, programming, trouble-shooting, managing complications and follow up Up-to-date with the latest in device technology Contains multiple graphics, device electrogram tracings, and radiographic images for clarity Includes video clips and over 150 multiple choice questions with extended answers on companion website, ideal for self test An invaluable resource for both the specialist pediatric cardiologist and the general cardiologist responsible for children with heart disease and pacing devices