Медицина - скачать книги или читать онлайн. Страница 120

This most widely used textbook in the field has been thoroughly revised and updated to reflect changes in the health care industry and the renewed focus on health care information technology initiatives. Two new chapters cover Federal efforts to enhance quality of patient care through the use of health care information technology and strategy considerations. Additionally, reflecting the increased focus on global health, the book features an international perspective on health care information technology. Case studies of organizations experiencing management-related information system challenges have been updated and several new cases have been added. These reality-based cases are designed to stimulate discussion among students and enable them to apply concepts in the book to real-life scenarios. The book's companion Web site features lecture slides, a test bank, and other materials to enhance students' understanding.

Guide to Ruminant Anatomy: Dissection and Clinical Aspectspresents a concise, clinically relevant reference to goat and cattle anatomy, with color schematic illustrations and embalmed arterially injected prosection images for comparison. Offers 244 color images depicting goat and cattle anatomy Provides selected line drawings correlated to dissection images of embalmed arterially injected specimens Takes a practical approach, with material organized by body system within each region Demonstrates the clinical relevance of basic anatomy Poses review questions in each chapter, with answers and videos provided on a companion website

This book presents advances in the field of neuronal mitochondria – functions, relation to therapeutics, and pharmacology. For scientists and researchers in both industry and academia, this book provides detailed discussion, examples, and approaches, to illustrate the potential of mitochondria as therapeutic targets for neuronal diseases. • Helps readers understand the regulation of mitochondrial cellular processes, such as substrate metabolism, energy production, and programmed versus sporadic cell death • Offers insights on the development of strategies for targeted therapeutic approaches and potential personalized treatments • Includes examples of mitochondrial drugs, development, and mitochondria-targeted approaches for more efficient treatment methods and further developments in the field • Covers the model systems and approaches needed for the development of new drugs for the central nervous system to provide potential modern therapeutics for neurodegenerative disorders

Now in its second edition, this practical guide offers clear-headed guidance to the successful application of catheter ablation for atrial fibrillation. This book concentrates on clinically-relevant information that providers can put to immediate use caring for patients. Takes a clear-headed practical approach to ablation of atrial fibrillation – long on actionable, clinically-relevant guidance, succinct and to-the-point on the theory behind the procedure Edited by three leading, internationally-known electrophysiologists with extensive experience in ablation for atrial fibrillation Written by international team of experts reflecting global best practices from centers with considerable experience in the use of catheter ablation Format designed to serve the needs of electrophysiologists regardless of experience, electrophysiology fellows, electrophysiology nurses and lab technical staff Covers hot topics such as new noninvasive imaging techniques, the treatment of challenging left atrial flutters, options for persistent atrial fibrillation and when a redo ablation is needed; and novel application of ablation targeting the autonomic nervous system

Presents an overview of the complex biological systems used within a global public health setting and features a focus on malaria analysis Bridging the gap between agent-based modeling and simulation (ABMS) and geographic information systems (GIS), Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology provides a useful introduction to the development of agent-based models (ABMs) by following a conceptual and biological core model of Anopheles gambiae for malaria epidemiology. Using spatial ABMs, the book includes mosquito (vector) control interventions and GIS as two example applications of ABMs, as well as a brief description of epidemiology modeling. In addition, the authors discuss how to most effectively integrate spatial ABMs with a GIS. The book concludes with a combination of knowledge from entomological, epidemiological, simulation-based, and geo-spatial domains in order to identify and analyze relationships between various transmission variables of the disease. Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology also features: Location-specific mosquito abundance maps that play an important role in malaria control activities by guiding future resource allocation for malaria control and identifying hotspots for further investigation Discussions on the best modeling practices in an effort to achieve improved efficacy, cost-effectiveness, ecological soundness, and sustainability of vector control for malaria An overview of the various ABMs, GIS, and spatial statistical methods used in entomological and epidemiological studies, as well as the model malaria study A companion website with computer source code and flowcharts of the spatial ABM and a landscape generator tool that can simulate landscapes with varying spatial heterogeneity of different types of resources including aquatic habitats and houses Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology is an excellent reference for professionals such as modeling and simulation experts, GIS experts, spatial analysts, mathematicians, statisticians, epidemiologists, health policy makers, as well as researchers and scientists who use, manage, or analyze infectious disease data and/or infectious disease-related projects. The book is also ideal for graduate-level courses in modeling and simulation, bioinformatics, biostatistics, public health and policy, and epidemiology.

Edited by a team of the world’s leading interventional cardiologists and educators, this new book is created with an eye to giving the reader a solid, practical, and clinically focused understanding of this important class of drugs, from basic science to a clear-headed discussion of complex topics such as combination therapies, drug-to-drug interactions, and resistance to antiplatelet agents. This important new book: Begins with a concise but thorough discussion of platelet biology and pathophysiology so that readers understand how antiplatelet agents work and why they produce such a varied range of complications, from minor GI upset to potentially life-threatening conditions such as neutropenia, a critical shortage of white blood cells. Thoroughly covers platelet function testing, including novel techniques. Clarifies current best practice regarding the use of antiplatelet agents in both chronic and acute cardiovascular disease. Reviews all types of antiplatelet agents – from aspirin to recently approved drugs – including indications, clinical outcomes, and side effects. Written by an international “who’s who” of experts in the field, Antiplatelet Therapy in Cardiovascular Disease also includes an entire section covering the use of antiplatelet drugs in PCIs, including percutaneous valve repair, which makes this text particularly essential to interventional cardiologists.

With a focus on case studies of R&D programs in a variety of disease areas, the book highlights fundamental productivity issues the pharmaceutical industry has been facing and explores potential ways of improving research effectiveness and efficiency. • Takes a comprehensive and holistic approach to the problems and potential solutions to drug compound attrition • Tackles a problem that adds billions of dollars to drug development programs and health care costs • Guides discovery and development scientists through R&D stages, teaching requirements and reasons why drugs can fail • Discusses potential ways forward utilizing new approaches and opportunities to reduce attrition

Botulinum Toxins: Cosmetic and Clinical Applications provides a comprehensive and in-depth review of the use of botulinum toxin for aesthetic procedures and medical applications as a stand-alone treatment and as part of combination therapy. Now a mainstay of cosmetic dermatologic practice, the range of available toxins and their varied applications has grown considerably in recent years requiring the practitioner to carefully consider what approach best suits the needs of their patient. This new book, written by international expert authors, provides guidance to help you refine your technique, add new procedures to your practice, and provide optimal results. This book: Offers guidance on best-practice approaches with botulinum toxin, helping create cutting edge, tailored treatment plans for each patient Benefits from a wealth of color images, procedural videos, and expert tips and tricks Takes a region oriented approach, providing guidance on treatment of the; glabella, forehead, periocular and perioral areas, and contouring of the lower face and lower leg and calf, and neck rejuvenation Contains a thorough review of non-cosmetic treatments such as correction of facial asymmetry, and treatment of axillary hyperhidrosis, plus palm, sole, and craniofacial hyperhidrosis Covers exciting new topics, such as future injectables, topical botulinum toxin, and facial contouring including treatment for benign masseter hypertrophy Discusses combination therapy of botulinum toxin with other non-surgical procedures such as hyaluronic acid (HA) or filler substances, light and laser sources, and other energy-based therapies Includes considerations for darker skin types Offer your patients the best care, stay on top of cutting edge techniques, and avoid pitfalls with coverage of practical tips and real cases. Botulinum Toxins in Dermatology: Cosmetic and Clinical Applications provides best-practice guidance on the contemporary use of botulinum toxin in isolation and in combination.

Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to find a new drug, and also an individual story of a drug discovery can initiate and help new discoveries. Volume III is a continuation of the successful book series with new examples of established and recently introduced drugs. The major part of the book is written by key inventors either as a case study or a study of an analogue class. With its wide range across a variety of therapeutic fields and chemical classes, this is of interest to virtually every researcher in drug discovery and pharmaceutical chemistry, and – together with the previous volumes – constitutes the first systematic approach to drug analogue development.

Esophageal Cancer and Barrett’s Esophagus, 3E, focuses on these two common and key conditions that affect the esophagus, providing expert guidance to their pathogenesis, cause, prevention, diagnosis and clinical management. Top international names in the field examine each of the many issues involved, using the very latest evidence-based research, and clear, didactic advice allows the reader to understand the best methods of diagnosis and clinical management of each condition – whether early or late stage. Well-illustrated and fully revised to include the latest in ACG/ASG/UEGW guidelines, it is the perfect consultation tool for gastroenterologists and oncologists managing patients with cancer of the esophagus. It is also ideal for teaching residents and fellows optimum patient management, and for identifying areas requiring future research.

Inflammatory Bowel Diseases: A Clinician’s Guide provides practical guidance for the diagnosis and management of those suspected or known to have one of the forms of these complex diseases. It is perfect both for gastroenterology trainees learning to care for these patients and the experienced physician as a concise and practical resource for day to day use. Written by the experts, Inflammatory Bowel Diseases: A Clinician’s Guide is an essential tool for all gastroenterologists managing patients with inflammatory bowel disease.

Bladder Cancer: Diagnosis and Clinical Management is a 100% clinically-focused guide to bladder cancer, providing practical, modern and evidence-based guidance to the latest in diagnosis and management of the condition. It differs from other books in its complete clinical focus as opposed to a heavy analysis of pathogenesis or basic science. As a result, practicing urologists and oncologists in the clinical setting will find it an essential resource to consult. In addition to the latest in diagnostic tools and imaging methods, core focus is on the management of each form of cancer at its various stages with up to date genomic data and targeted therapies. Both drug therapies and the range of surgical options are covered, ensuring that this is the perfect tool for clinicians to consult when considering which type of management program is appropriate for each individual patient. A key addition is the final section dedicated to optimizing health care delivery, featuring chapters on highly topical issues such as quality of life, patient advocacy and surgical education. Full color throughout, and packed with excellent images, each chapter contains concise and didactic practical tips and tricks to enrich the reading experience, in addition to management algorithms and the very latest guidelines from the ASCO, AUA, ESMO and EAU concerning clinical management of bladder cancer.