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Our understanding of the ‘tree of life’, with powerful implications for human genetics, human health and our own human nature, has recently completely changed.This book is about a new method of telling the story of life on earth – through molecular phylogenetics. It involves a fairly simple method – the reading of the deep history of life by looking at the variation in protein molecules found in living organisms. For instance, we now know that roughly eight per cent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection.In The Tangled Tree, acclaimed science writer David Quammen chronicles these discoveries through the lives of the researchers who made them – such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about ‘mosaic’ creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.Quammen explains how molecular studies of evolution have brought startling recognitions about the tangled tree of life – including where we humans fit into it. Thanks to new technologies, we now have the ability to alter even our genetic composition – through sideways insertions, as nature has long been doing. The Tangled Tree is a brilliant exploration of our transformed understanding of evolution and of life’s history itself.

In this provocative, mind-bending international bestseller, prize-winning neuroscientist Mariano Sigman reveals his life’s work exploring the inner workings of the human brain.Sigman's ambition is to explain the mind so that we can understand ourselves and others more deeply. He shows how we form ideas during our first days of life, how we give shape to our fundamental decisions, how we dream and imagine, why we feel certain emotions, how the brain transforms and how who we are changes with it. Sigman looks at the development of language, how bilingualism helps us to think and our notions of what is good and fair develop far earlier than we think.Building on his awe-inspiring TED talk and spanning biology, physics, philosophy and medicine as well as gastronomy, magic, music, chess, literature and art, The Secret Life of the Mind revolutionizes how neuroscience serves us in our lives, revealing how the infinity of neurons inside our brains manufacture how we perceive, reason, feel, dream and communicate.

Our use of light at night is negatively affecting the natural world in ways we’re barely beginning to study. Meanwhile, our physical, psychological, and spiritual health are significantly influenced by darkness or a lack thereof; it’s not a matter of using light at night or not, but rather when and where, how and how much.We live awash in artificial light. Since the 1930s its increase has been gradual enough that it would be easy to imagine our nights are as dark, or nearly so, as they ever were. But today some three-quarters of Europeans and Americans no longer experience real night and can’t imagine real darkness—and nearly all of us live in areas considered polluted by light.In ways we’ve long understood, in others we’re just beginning understand, night’s natural darkness has always been invaluable for our spiritual health and the health of the natural world, and every living creature suffers from its loss.In Geography of Night, Paul Bogart investigates what we mean when we talk about the different shades of darkness, about what we’ve lost, what we still have, what we might regain. He travels from our brightest nights to our darkest, from the intensely-lit cities where public lighting as we know it began, to the sites where real darkness might still remain. Encountering scientists, physicians, activists and writers, Bogart discusses how our use of light at night is negatively affecting the natural world in ways we’re barely beginning to study; how human physical, psychological, and spiritual health are significantly influenced by darkness or a lack thereof; and how it’s not a matter of using light at night or not, but rather when and where, how and how much.A beautiful invocation of our constant companion, the night, which returns every day of our lives, this book reminds us of the power and mystery of the dark.

Winner of the Guardian First Book Award 2011Winner of the Pulitzer Prize for Non-fiction 2011Shortlisted for the Wellcome Trust Book PrizeShortlisted for the Duff Cooper PrizeNow, as cancer becomes an ever more universal experience, the need to understand it, and its treatment, has never been more compelling. In this groundbreaking and award-winning account Siddhartha Mukherjee tells the fascinating story of our relationship with this disease. From brutal early surgical treatments, to Sidney Farber’s hugely risky discovery of chemotherapy, to the author’s treatment of his own patients, he reveals how far we have come in solving one of science's great mysteries and offers a fascinating glimpse of our future progress.

The Science of Secrecy from Ancient Egypt to Quantum CryptographyFrom the best-selling author of Fermat’s Last Theorem, The Code Book is a history of man’s urge to uncover the secrets of codes, from Egyptian puzzles to modern day computer encryptions.As in Fermat’s Last Theorem, Simon Singh brings life to an anstonishing story of puzzles, codes, languages and riddles that reveals man’s continual pursuit to disguise and uncover, and to work out the secret languages of others.Codes have influenced events throughout history, both in the stories of those who make them and those who break them. The betrayal of Mary Queen of Scots and the cracking of the enigma code that helped the Allies in World War II are major episodes in a continuing history of cryptography. In addition to stories of intrigue and warfare, Simon Singh also investigates other codes, the unravelling of genes and the rediscovery of ancient languages and most tantalisingly, the Beale ciphers, an unbroken code that could hold the key to a $20 million treasure.Note that it has not been possible to include the same picture content that appeared in the original print version.

Over the years, millions of school children must have written out their address in the same way – their house number and street, their town, their country, their continent, planet Earth, the universe…

The noted cultural anthropologist and author of 'The Interpretation of Cultures' deepens our understanding of human societies through the intimacies of 'local knowledge.'This sequel to The Interpretation of Cultures is a collection of essays which reject large abstractions, going beyond the mere translation of one culture into another, and looks at the underlying, compartmentalized reality.

The extraordinary story of the solving of a puzzle that has confounded mathematicians since the 17th century. The solution of Fermat’s Last Theorem is the most important mathematical development of the 20th century.In 1963 a schoolboy browsing in his local library stumbled across the world’s greatest mathematical problem: Fermat’s Last Theorem, a puzzle that every child can understand but which has baffled mathematicians for over 300 years. Aged just ten, Andrew Wiles dreamed that he would crack it. Wiles’s lifelong obsession with a seemingly simple challenge set by a long-dead Frenchman is an emotional tale of sacrifice and extraordinary determination. In the end, Wiles was forced to work in secrecy and isolation for seven years, harnessing all the power of modern maths to achieve his childhood dream. Many before him had tried and failed, including a 18-century philanderer who was killed in a duel. An 18-century Frenchwoman made a major breakthrough in solving the riddle, but she had to attend maths lectures at the Ecole Polytechnique disguised as a man since women were forbidden entry to the school. A remarkable story of human endeavour and intellectual brilliance over three centuries, Fermat ‘s Last Theorem will fascinate both specialist and general readers.

This edition does not include illustrations.The story of a man’s obsession with whales, which takes him on a personal, historical and biographical journey – from his childhood to his fascination with Moby-Dick and his excursions whale-watching.All his life, Philip Hoare has been obsessed by whales, from the gigantic skeletons in London’s Natural History Museum to adult encounters with the wild animals themselves. Whales have a mythical quality – they seem to elide with dark fantasies of sea-serpents and antediluvian monsters that swim in our collective unconscious.In ‘Leviathan’, Philip Hoare seeks to locate and identify this obsession. What impelled Melville to write ‘Moby-Dick’? After his book in 1851, no one saw whales in quite the same way again.This book is an investigation into what we know little about – dark, shadowy creatures who swim below the depths, only to surface in a spray of spume. More than the story of the whale, it is also the story of our own obsessions.

The bestselling author of Fermat’s Last Theorem and The Code Book tells the story of the brilliant minds that deciphered the mysteries of the Big Bang. A fascinating exploration of the ultimate question: how was our universe created?Albert Einstein once said: ‘The most incomprehensible thing about the universe is that it is comprehensible.’ Simon Singh believes geniuses like Einstein are not the only people able to grasp the physics that govern the universe. We all can.As well as explaining what the Big Bang theory actually is and why cosmologists believe it is an accurate description of the origins of the universe, this book is also the fascinating story of the scientists who fought against the established idea of an eternal and unchanging universe. Simon Singh, renowned for making difficult ideas much less daunting than they first seem, is the perfect guide for this journey.Everybody has heard of the Big Bang Theory. But how many of us can actually claim to understand it? With characteristic clarity and a narrative peppered with anecdotes and personal histories of those who have struggled to understand creation, Simon Singh has written the story of the most important theory ever.

Full of spleen, this will be a hilarious, invigorating and informative journey through the world of Bad Science.When Dr Ben Goldacre saw someone on daytime TV dipping her feet in an 'Aqua Detox' footbath, releasing her toxins into the water, turning it brown, he thought he'd try the same at home. 'Like some kind of Johnny Ball cum Witchfinder General', using his girlfriend's Barbie doll, he gently passed an electrical current through the warm salt water. It turned brown. In his words: 'before my very eyes, the world's first Detox Barbie was sat, with her feet in a pool of brown sludge, purged of a weekend's immorality.'Dr Ben Goldacre is the author of the Bad Science column in the Guardian. This book will be about all the 'bad science' we are constantly bombarded with in the media and in advertising. At a time when science is used to prove everything and nothing, everyone has their own 'bad science' moments – from the useless pie-chart on the back of cereal packets to the use of the word 'visibly' in cosmetics ads. This book will help people to quantify their instincts – that a lot of the so-called 'science' which appears in the media and in advertising is just wrong or misleading. It will be satirical and amusing – exposing the ridiculous – but it will also provide the reader with the facts they need.Full of spleen, this will be a hilarious, invigorating and informative journey through the world of Bad Science.